Principles of Experimental Psychopathology celebrates the contributions of Brendan A. Maher to the development and emergence of experimental psychopathology as a sub-discipline of psychological science. Several current research programs are discussed, and contributors provide rich examples of how the methods of experimental psychology and allied disciplines have been applied to the study of schizophrenia and other psychopathological conditions through a strong understanding of normative processes, genetics, and neuroscience.

In the opening chapter of the volume, Maher discusses his view of the formation of delusional thought and the methodological approach he has taken in studying this area. Maher's influence is evident throughout the volume, as contributors explore schizophrenia and other disorders from alternative methodological viewpoints.

This book will be an invaluable resource for advanced scholars and graduate students alike who are committed to psychological science as a laboratory-based discipline that has real-world implications.

Table of Contents



Brendan A. Maher: A Biographical Sketch
—Mark F. Lenzenweger

—Mark F. Lenzenweger and Jill M. Hooley

I. Experimental Psychopathology of Delusions

  1. Psychopathology and Delusions: Reflections on Methods and Models
    —Brendan A. Maher

II. Schizophrenia as Seen From the Experimental Psychopathology Vantage Point

  1. Strengthening the Evidence for Genetic Factors in Schizophrenia (Without Abetting Genetic Discrimination)
    —Irving I. Gottesman and James L. Reilly
  2. The Role of Motor Behavior in the Pathogenesis of Schizophrenia
    —Theo C. Manschreck
  3. Negative Symptoms, Neuromotor Abnormalities, and Vulnerability to Schizophrenia
    —Robert H. Dworkin, Elna M. Nagasako, Scott C. Clark, William C. Wirshing, Xavier F. Amador, Jack M. Gorman, and Lyman C. Wynne
  4. Spatial Working Memory Function in Schizophrenia
    —Sohee Park and Junghee Lee
  5. Understanding the Employment Rate of People With Schizophrenia: Different Approaches Lead to Different Implications for Policy
    —Crystal R. Blyler

III. Methodological Challenges in Probing Schizophrenia

  1. The Neuropsychological Study of Schizophrenia: A Methodological Perspective
    —Milton E. Strauss and Ann Summerfelt
  2. Methodological Excursions in Pursuit of a Somatosensory Dysfunction in Schizotypy and Schizophrenia
    —Mark F. Lenzenweger, Ken Nakayama, and Bernard P. Chang
  3. Pain Insensitivity in Relatives of Patients With Schizophrenia and Bipolar Disorder
    —Jill M. Hooley and Richard J. Chung

IV. Methodological Advances in the Study of Psychopathology

  1. Less Is Truly More: Psychopathology Research in the 21st Century
    —Philip S. Holzman
  2. Event-Related Brain Potential Indices of Memory Biases in Major Depression
    —Patricia J. Deldin, Augusta Shestyuk, and Pearl H. Chiu
  3. Magnetic Resonance Methods for the Study of Psychopathology
    —Deborah A. Yurgelun-Todd and Staci A. Gruber
  4. Functional Neuroimaging Investigations of Working Memory Deficits in Schizophrenia: Reconciling Discrepant Findings
    —Dara S. Manoach

V. Using Temperament and Cognition as Leverage in Psychopathology Research

  1. Surprise and Uncertainty
    —Jerome Kagan
  2. Electrodermal Hyporeactivity in Psychopathy: Does It Reflect Disinhibition, Low Anxiety, or Both?
    —Don C. Fowles
  3. Experimental Approaches to the Recovered Memory Controversy
    —Richard J. McNally

Author Index

Subject Index

About the Editors